From LedHed's Wiki
GPO
User Configuration -> Preferences -> Windows Settings -> Registry
New Registry Item
Action: Update Hive: HKCU Key path: Control\Desktop Value Name: SCRNSAVE.EXE Value Type: REG_SZ Value Data: C:\Windows\system32\scrnsave.scr
Common Tab -> Item-Level targeting
the registry value HKCU\Control Panel\Desktop\SCRNSAVE.EXE does not exist